Jamie and Dylan, on opposite coasts, break up with their lovers: each separately vows to stay out of emotional entanglements. So when Jamie recruits Dylan to run GQ's art department in NYC - and she's the only person he knows in Manhattan - they decide to be friends with sexual benefits. It works well until Jamie meets a pediatric cardiologist who just might be a match, and Dylan invites her to come home with him to LA for Thanksgiving. He may be jealous of the doc, she may be sending new vibes in Dylan's direction, but can either see the signals? And, is it inevitable that life imitates art?